Genotype-based test in mapping cis-regulatory variants from allele-specific expression data.

Genotype-based test in mapping cis-regulatory variants from allele-specific expression data.

Identifying and understanding the impact of gene regulatory variation is of considerable importance in evolutionary and medical genetics; such variants are thought to be responsible for human-specific adaptation and to have an important role in genetic disease. Regulatory variation in cis is readily...

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Bibliographic Details
Main Authors: Jean Francois Lefebvre, Emilio Vello, Bing Ge, Stephen B Montgomery, Emmanouil T Dermitzakis, Tomi Pastinen, Damian Labuda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3369843?pdf=render

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http://europepmc.org/articles/PMC3369843?pdf=render

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