Development of a Safe and Effective Vaccinia Virus Oncolytic Vector WR-Δ4 with a Set of Gene Deletions on Several Viral Pathways

Despite the effectiveness of classic treatments and available diagnostic tools, cancer continues to be a leading world health problem, with devastating cancer-related death rates. Advances in oncolytic virotherapy have shown promise as potentially effective treatment options in the fight against can...

Full description

Bibliographic Details
Main Authors: Ernesto Mejías-Pérez, Liliana Carreño-Fuentes, Mariano Esteban
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770517300499