Dynamics of natural product Lupenone as a potential fusion inhibitor against the spike complex of novel Semliki Forest Virus.

The Semliki Forest Virus (SFV) is an RNA virus with a positive-strand that belongs to the Togaviridae family's Alphavirus genus. An epidemic was observed among French troops stationed in the Central African Republic, most likely caused by the SFV virus. The two transmembrane proteins El and E2...

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Main Authors: Nobendu Mukerjee, Anubhab Das, Swastika Maitra, Arabinda Ghosh, Prattusha Khan, Athanasios Alexiou, Abhijit Dey, Debabrat Baishya, Faizan Ahmad, Punya Sachdeva, Muhanna K Al-Muhanna
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0263853