NLRP3-dependent lipid droplet formation contributes to posthemorrhagic hydrocephalus by increasing the permeability of the blood–cerebrospinal fluid barrier in the choroid plexus

Brain hemorrhage: Causes of fluid build-up on the brain Inhibiting a key inflammatory protein and thereby protecting the blood-brain barrier following brain hemorrhage may prevent the build-up of fluid on the brain (hydrocephalus). Using rat models and cell cultures, Yujie Chen and Hua Feng at the T...

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Bibliographic Details
Main Authors: Zhaoqi Zhang, Peiwen Guo, Liang Liang, Shiju Jila, Xufang Ru, Qiang Zhang, Jingyu Chen, Zhi Chen, Hua Feng, Yujie Chen
Format: Article
Language:English
Published: Nature Publishing Group 2023-03-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-00955-9