Mesenchymal Stem Cell-Derived Extracellular Vesicles Improve the Renal Microvasculature in Metabolic Renovascular Disease in Swine

Background: Extracellular vesicles (EVs) released from mesenchymal stem/stromal cells (MSCs) mediate their paracrine effect, but their efficacy to protect the microcirculation of the kidney is unknown. Using a novel swine model of unilateral renovascular disease (RVD) complicated by metabolic syndro...

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Bibliographic Details
Main Authors: Alfonso Eirin, Xiang-Yang Zhu, Sreela Jonnada, Amir Lerman, Andre J. van Wijnen, Lilach O. Lerman
Format: Article
Language:English
Published: SAGE Publishing 2018-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689718780942