Sex Differences in Photoprotective Responses to 1,25-Dihydroxyvitamin D3 in Mice Are Modulated by the Estrogen Receptor-β

Sex Differences in Photoprotective Responses to 1,25-Dihydroxyvitamin D3 in Mice Are Modulated by the Estrogen Receptor-β

Susceptibility to photoimmune suppression and photocarcinogenesis is greater in male than in female humans and mice and is exacerbated in female estrogen receptor-beta knockout (ER-β−/−) mice. We previously reported that the active vitamin D hormone, 1,25-dihydroxyvitamin D3 (1,25(OH)2D), applied to...

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Bibliographic Details
Main Authors: Wannit Tongkao-on, Chen Yang, Bianca Y. McCarthy, Warusavithana G. Manori De Silva, Mark S. Rybchyn, Clare Gordon-Thomson, Katie M. Dixon, Gary M. Halliday, Vivienne E. Reeve, Rebecca S. Mason
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
1α,25-dihydroxyvitaminD3
photoprotection
DNA damage
cyclobutane pyrimidine dimers
edema
photoimmune suppression
Online Access:https://www.mdpi.com/1422-0067/22/4/1962

Internet

https://www.mdpi.com/1422-0067/22/4/1962

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