Extended-release metformin improves cognitive impairment in frail older women with hypertension and diabetes: preliminary results from the LEOPARDESS Study

Extended-release metformin improves cognitive impairment in frail older women with hypertension and diabetes: preliminary results from the LEOPARDESS Study

Abstract Background Women have a high risk of frailty independently of age and menopause state. Diabetes and hypertension increase the risk of frailty and cognitive impairment. Metformin has been employed in post-menopausal women and some reports have shown encouraging effects in terms of attenuated...

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Bibliographic Details
Main Authors: Pasquale Mone, Giuseppe Martinelli, Angela Lucariello, Anna Luisa Leo, Anna Marro, Stefano De Gennaro, Stefania Marzocco, Divina Moriello, Salvatore Frullone, Luigi Cobellis, Gaetano Santulli
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Cardiovascular Diabetology
Subjects:
Aging
Biguanides
Cognitive dysfunction
Frailty
Hyperglycemia
Menopause
Online Access:https://doi.org/10.1186/s12933-023-01817-4

Internet

https://doi.org/10.1186/s12933-023-01817-4

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