Effect of corticosubcortical iron deposition on dysfunction in CADASIL is mediated by white matter microstructural damage

Effect of corticosubcortical iron deposition on dysfunction in CADASIL is mediated by white matter microstructural damage

Iron dysregulation may attenuate cognitive performance in patients with CADASIL. However, the underlying pathophysiological mechanisms remain incompletely understood. Whether white matter microstructural changes mediate these processes is largely unclear. In the present study, 30 cerebral autosomal...

Full description

Bibliographic Details
Main Authors: Xiuqin Jia, Yingying Li, Yunqing Ying, Xuejia Jia, Weijun Tang, Yueyan Bian, Jiajia Zhang, Danny J.J. Wang, Xin Cheng, Qi Yang
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:NeuroImage: Clinical
Subjects:
Quantitative susceptibility mapping (QSM)
Peak width of skeletonized mean diffusivity (PSMD)
CADASIL
Cerebral small vessel disease (cSVD)
Iron deposition
Cognitive deficit
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158223001766

Internet

http://www.sciencedirect.com/science/article/pii/S2213158223001766

Similar Items