Meta-Analysis Identification of Highly Robust and Differential Immune-Metabolic Signatures of Systemic Host Response to Acute and Latent Tuberculosis in Children and Adults

Meta-Analysis Identification of Highly Robust and Differential Immune-Metabolic Signatures of Systemic Host Response to Acute and Latent Tuberculosis in Children and Adults

Background: Whole blood expression profiling is a mainstay for delineating differential diagnostic signatures of infection yet is subject to high variability that reduces power and complicates clinical usefulness. To date, confirmatory high confidence expression profiling signatures for clinical use...

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Detalles Bibliográficos
Main Authors: Saikou Y. Bah, Thorsten Forster, Paul Dickinson, Beate Kampmann, Peter Ghazal
Formato: Artigo
Idioma:English
Publicado: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Genetics
Subjects:
tuberculosis
meta-analysis
immunity
systemic responses
microarray
bioinformatics
Acceso en liña:https://www.frontiersin.org/article/10.3389/fgene.2018.00457/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00457/full

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