AKR1B1 drives hyperglycemia-induced metabolic reprogramming in MASLD-associated hepatocellular carcinoma

AKR1B1 drives hyperglycemia-induced metabolic reprogramming in MASLD-associated hepatocellular carcinoma

Background & Aims: The mechanism behind the progressive pathological alteration in metabolic dysfunction-associated steatotic liver disease/steatohepatitis (MASLD/MASH)-associated hepatocellular carcinoma (HCC) is poorly understood. In the present study, we investigated the role of the polyo...

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Bibliographic Details
Main Authors: NP Syamprasad, Siddhi Jain, Bishal Rajdev, Samir Ranjan Panda, Gangasani Jagadeesh Kumar, Khaja Moinuddin Shaik, P.A. Shantanu, Veerabhadra Swamy Challa, Sachin B. Jorvekar, Roshan M. Borkar, Jayathirtha Rao Vaidya, Dinesh Mani Tripathi, V.G.M. Naidu
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:JHEP Reports
Subjects:
MASLD/MASH
HCC
Metabolism
Warburg effect
NARI-29
epalrestat
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923003051

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http://www.sciencedirect.com/science/article/pii/S2589555923003051

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