Activating Transcription Factor 3 Diminishes Ischemic Cerebral Infarct and Behavioral Deficit by Downregulating Carboxyl-Terminal Modulator Protein

Activating Transcription Factor 3 Diminishes Ischemic Cerebral Infarct and Behavioral Deficit by Downregulating Carboxyl-Terminal Modulator Protein

Activating transcription factor 3 (ATF3) is a stress-induced transcription factor and a familiar neuronal marker for nerve injury. This factor has been shown to protect neurons from hypoxic insult in vitro by suppressing carboxyl-terminal modulator protein (CTMP) transcription, and indirectly activa...

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Bibliographic Details
Main Authors: Mei-Han Kao, Chien-Yu Huang, Wai-Mui Cheung, Yu-Ting Yan, Jin-Jer Chen, Yuan-Soon Ho, Chung Y. Hsu, Teng-Nan Lin
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
stroke
apoptosis
Akt/PKB
ATF3
CTMP
gene regulation
Online Access:https://www.mdpi.com/1422-0067/24/3/2306

Internet

https://www.mdpi.com/1422-0067/24/3/2306

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