The role of KLRG1: a novel biomarker and new therapeutic target

The role of KLRG1: a novel biomarker and new therapeutic target

Abstract Killer cell lectin-like receptor G1 (KLRG1) is an immune checkpoint receptor expressed predominantly in NK and T-cell subsets that downregulates the activation and proliferation of immune cells and participates in cell-mediated immune responses. Accumulating evidence has demonstrated the im...

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Bibliographic Details
Main Authors: Yakun Zhang, Shuang Chen, Xinyi Tang, Yu Peng, Tingting Jiang, Xiaomei Zhang, Jun Li, Yao Liu, Zailin Yang
Format: Article
Language:English
Published: BMC 2024-06-01
Series:Cell Communication and Signaling
Subjects:
KLRG1
Immune checkpoint proteins
Biomarker
Therapeutic target
Tumor immunotherapy
Online Access:https://doi.org/10.1186/s12964-024-01714-7

Internet

https://doi.org/10.1186/s12964-024-01714-7

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