Intra-tumoral infiltration of adipocyte facilitates the activation of antitumor immune response in pancreatic ductal adenocarcinoma

Intra-tumoral infiltration of adipocyte facilitates the activation of antitumor immune response in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal malignancy that is characterized by an immunosuppressive microenvironment. The immune suppression in PDAC is largely driven by heterogeneous stromal and tumor cells. However, how adipocyte in the tumor microenvironment (TME) is related to the...

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Bibliographic Details
Main Authors: Xiaomeng Liu, Jiang Liu, Jin Xu, Bo Zhang, Miaoyan Wei, Jialin Li, Hang Xu, Xianjun Yu, Wei Wang, Si Shi
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Translational Oncology
Subjects:
Pancreatic cancer
Adipocyte infiltration
Cytokine infiltration
Antitumor immune response
Tumor microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523322002200

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http://www.sciencedirect.com/science/article/pii/S1936523322002200

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