Rare evolution of CSF3R-mutated chronic neutrophilic leukemia to t(4;12)(q12;p13) acute myeloid leukemia with SETBP1 mutation

Rare evolution of CSF3R-mutated chronic neutrophilic leukemia to t(4;12)(q12;p13) acute myeloid leukemia with SETBP1 mutation

Chronic neutrophilic leukemia (CNL) is a rare myeloproliferative disease accompanied by mutations in CSF3R. Here, we present a patient with CNL who developed to acute myeloid leukemia (AML) at the same time that a t(4;12)(q12;p13) translocation appeared. The uniqueness of this cytogenetic abnormalit...

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Bibliographic Details
Main Authors: Maki Hirao, Kentaro Watanabe, Yuiko Tsukada, Hisako Kunieda, Makoto Osada, Kohei Yamazaki, Ryunosuke Denda, Shinichiro Okamoto, Takahide Kikuchi
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Leukemia Research Reports
Subjects:
Chronic neutrophilic leukemia
Acute myeloid leukemia
t(4 ； 12)(q12 ； p13)
SETBP1
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048922000231

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http://www.sciencedirect.com/science/article/pii/S2213048922000231

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