Priming of HIV-1-specific CD8+ T cells with strong functional properties from naïve T cellsResearch in context

Priming of HIV-1-specific CD8+ T cells with strong functional properties from naïve T cellsResearch in context

Background: HIV-1-specific CD8+ T cells are required for immune suppression of HIV-1 replication and elimination of the associated viral reservoirs. However, effective induction of functional HIV-1-specific CD8+ T cells from naïve cells remains problematic in the setting of human vaccine trials. In...

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Bibliographic Details
Main Authors: Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Anna Lissina, Takuya Yamamoto, Victor Appay, Masafumi Takiguchi
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419302233

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http://www.sciencedirect.com/science/article/pii/S2352396419302233

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