DNA-PKcs promotes sepsis-induced multiple organ failure by triggering mitochondrial dysfunction

DNA-PKcs promotes sepsis-induced multiple organ failure by triggering mitochondrial dysfunction

Introduction: Multiple organ failure is the commonest cause of death in septic patients. Objectives: This study was undertaken in an attempt to elucidate the functional importance of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) on mitochondrial dysfunction associated with the developmen...

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Bibliographic Details
Main Authors: Rongjun Zou, Jun Tao, Junxiong Qiu, Huimin Lu, Jianhua Wu, Hang Zhu, Ruibing Li, David Mui, Sam Toan, Xing Chang, Hao Zhou, Xiaoping Fan
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Journal of Advanced Research
Subjects:
DNA-PKcs
MODS
Sepsis
Heart
Mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123222000273

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http://www.sciencedirect.com/science/article/pii/S2090123222000273

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