Adolescent pruning and stabilization of dendritic spines on cortical layer 5 pyramidal neurons do not depend on gonadal hormones

Pyramidal neurons in the neocortex receive a majority of their synapses on dendritic spines, whose growth, gain, and loss regulate the strength and identity of neural connections. Juvenile brains typically show higher spine density and turnover compared to adult brains, potentially enabling greater...

Full description

Bibliographic Details
Main Authors: Josiah R. Boivin, David J. Piekarski, A. Wren Thomas, Linda Wilbrecht
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Developmental Cognitive Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S187892931730169X