Crystal structure, spectral, thermo-gravimetric and antibacterial properties of Zn(Ⅱ) ofloxacin complex(氧氟沙星锌配合物的结构、光谱性质与抗菌活性)
合成了以氧氟沙星(ofloxacin，ofo)为配体的锌（Ⅱ)配合物Zn(ofo)2 (H2O) • 2H2O，报道了锌配合物的单晶结构：三斜晶系，P-1空间群，晶胞参数为a=9.306(1)Å，b=11.331(1)Å，c=17.787 (2) Å，α= 92.667(1)°，β = 94.898(2)°, γ= 92.071(2)°，V= 1865.1(3)Å3，Z=2，Dc = 1.496 mg • m-3，畸变的四方锥形配位几何构型，其中锥顶上的氧原子来自水分子，锥底的4个氧原子来自两个氧氟沙星的羧酸根和酮基；探讨了该配合物的红外光谱、紫外-可见光谱、固体荧光光谱性质，对配合物的热稳定...
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| Format: | Article |
| Language: | zho |
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Zhejiang University Press
2011-01-01
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| Series: | Zhejiang Daxue xuebao. Lixue ban |
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| Online Access: | https://doi.org/10.3785/j.issn.1008-9497.2011.01.017 |
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| author | SHIWei-wei(史维维) CHENWei(陈威) LEIQun-fang(雷群芳) WANGGuo-ping(王国平) HUANGFei-he(黄飞鹤) |
| author_facet | SHIWei-wei(史维维) CHENWei(陈威) LEIQun-fang(雷群芳) WANGGuo-ping(王国平) HUANGFei-he(黄飞鹤) |
| author_sort | SHIWei-wei(史维维) |
| collection | DOAJ |
| description | 合成了以氧氟沙星(ofloxacin，ofo)为配体的锌（Ⅱ)配合物Zn(ofo)2 (H2O) • 2H2O，报道了锌配合物的单晶结构：三斜晶系，P-1空间群，晶胞参数为a=9.306(1)Å，b=11.331(1)Å，c=17.787 (2) Å，α= 92.667(1)°，β = 94.898(2)°, γ= 92.071(2)°，V= 1865.1(3)Å3，Z=2，Dc = 1.496 mg • m-3，畸变的四方锥形配位几何构型，其中锥顶上的氧原子来自水分子，锥底的4个氧原子来自两个氧氟沙星的羧酸根和酮基；探讨了该配合物的红外光谱、紫外-可见光谱、固体荧光光谱性质，对配合物的热稳定性进行了研究；并利用液体稀释法测定了药物配体和配合物对两种革兰氏阳性菌和两种革兰氏阴性菌的体外抑制活性.结果表明配合物与药物配体的抗菌活性相近. |
| first_indexed | 2024-04-24T16:57:34Z |
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| id | doaj.art-81084070cd7d4a5ebe19317916462f1c |
| institution | Directory Open Access Journal |
| issn | 1008-9497 |
| language | zho |
| last_indexed | 2024-04-24T16:57:34Z |
| publishDate | 2011-01-01 |
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| series | Zhejiang Daxue xuebao. Lixue ban |
| spelling | doaj.art-81084070cd7d4a5ebe19317916462f1c2024-03-29T01:58:29ZzhoZhejiang University PressZhejiang Daxue xuebao. Lixue ban1008-94972011-01-01381687210.3785/j.issn.1008-9497.2011.01.017Crystal structure, spectral, thermo-gravimetric and antibacterial properties of Zn(Ⅱ) ofloxacin complex(氧氟沙星锌配合物的结构、光谱性质与抗菌活性)SHIWei-wei(史维维)0CHENWei(陈威)1LEIQun-fang(雷群芳)2WANGGuo-ping(王国平)HUANGFei-he(黄飞鹤)3Department of Chemistry, Zhejiang University, Hangzhou 310027, China(浙江大学 化学系，浙江 杭州 310027)Department of Chemistry, Zhejiang University, Hangzhou 310027, China(浙江大学 化学系，浙江 杭州 310027)Department of Chemistry, Zhejiang University, Hangzhou 310027, China(浙江大学 化学系，浙江 杭州 310027)Department of Chemistry, Zhejiang University, Hangzhou 310027, China(浙江大学 化学系，浙江 杭州 310027)合成了以氧氟沙星(ofloxacin，ofo)为配体的锌（Ⅱ)配合物Zn(ofo)2 (H2O) • 2H2O，报道了锌配合物的单晶结构：三斜晶系，P-1空间群，晶胞参数为a=9.306(1)Å，b=11.331(1)Å，c=17.787 (2) Å，α= 92.667(1)°，β = 94.898(2)°, γ= 92.071(2)°，V= 1865.1(3)Å3，Z=2，Dc = 1.496 mg • m-3，畸变的四方锥形配位几何构型，其中锥顶上的氧原子来自水分子，锥底的4个氧原子来自两个氧氟沙星的羧酸根和酮基；探讨了该配合物的红外光谱、紫外-可见光谱、固体荧光光谱性质，对配合物的热稳定性进行了研究；并利用液体稀释法测定了药物配体和配合物对两种革兰氏阳性菌和两种革兰氏阴性菌的体外抑制活性.结果表明配合物与药物配体的抗菌活性相近.https://doi.org/10.3785/j.issn.1008-9497.2011.01.017配合物氧氟沙星光谱性质结构分析抗菌活性 |
| spellingShingle | SHIWei-wei(史维维) CHENWei(陈威) LEIQun-fang(雷群芳) WANGGuo-ping(王国平) HUANGFei-he(黄飞鹤) Crystal structure, spectral, thermo-gravimetric and antibacterial properties of Zn(Ⅱ) ofloxacin complex(氧氟沙星锌配合物的结构、光谱性质与抗菌活性) Zhejiang Daxue xuebao. Lixue ban 配合物 氧氟沙星 光谱性质 结构分析 抗菌活性 |
| title | Crystal structure, spectral, thermo-gravimetric and antibacterial properties of Zn(Ⅱ) ofloxacin complex(氧氟沙星锌配合物的结构、光谱性质与抗菌活性) |
| title_full | Crystal structure, spectral, thermo-gravimetric and antibacterial properties of Zn(Ⅱ) ofloxacin complex(氧氟沙星锌配合物的结构、光谱性质与抗菌活性) |
| title_fullStr | Crystal structure, spectral, thermo-gravimetric and antibacterial properties of Zn(Ⅱ) ofloxacin complex(氧氟沙星锌配合物的结构、光谱性质与抗菌活性) |
| title_full_unstemmed | Crystal structure, spectral, thermo-gravimetric and antibacterial properties of Zn(Ⅱ) ofloxacin complex(氧氟沙星锌配合物的结构、光谱性质与抗菌活性) |
| title_short | Crystal structure, spectral, thermo-gravimetric and antibacterial properties of Zn(Ⅱ) ofloxacin complex(氧氟沙星锌配合物的结构、光谱性质与抗菌活性) |
| title_sort | crystal structure spectral thermo gravimetric and antibacterial properties of zn ii ofloxacin complex 氧氟沙星锌配合物的结构 光谱性质与抗菌活性 |
| topic | 配合物 氧氟沙星 光谱性质 结构分析 抗菌活性 |
| url | https://doi.org/10.3785/j.issn.1008-9497.2011.01.017 |
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