miR-197-3p Promotes Osteosarcoma Stemness and Chemoresistance by Inhibiting SPOPL

miR-197-3p Promotes Osteosarcoma Stemness and Chemoresistance by Inhibiting SPOPL

First-line treatment for osteosarcoma includes chemotherapy and surgery. However, the five-year survival rate of refractory osteosarcoma remains unsatisfactory. Osteosarcoma cancer stem cells, possessing stemness and chemoresistance, are one of the critical causes of poor response to chemotherapy. E...

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Bibliographic Details
Main Authors: Jingyong Zhang, Shubao Wang, Yang Bai, Aasi Mohammad Ali, Jiewen Deng, Yushi Chen, Yonghui Fu, Ming He
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Clinical Medicine
Subjects:
miR-197-3p
SPOPL
osteosarcoma
cancer stem cells
stemness
chemoresistance
Online Access:https://www.mdpi.com/2077-0383/12/3/1177

Internet

https://www.mdpi.com/2077-0383/12/3/1177

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