Non-Expressed Donor KIR3DL1 Alleles May Represent a Risk Factor for Relapse after T-Replete Haploidentical Hematopoietic Stem Cell Transplantation

Non-Expressed Donor KIR3DL1 Alleles May Represent a Risk Factor for Relapse after T-Replete Haploidentical Hematopoietic Stem Cell Transplantation

KIR3DL1 alleles are expressed at different levels on the natural killer (NK) cell surface. In particular, the non-expressed KIR3DL1*004 allele appears to be common in Caucasian populations. However, the overall distribution of non-expressed KIR3DL1 alleles and their clinical relevance after T-replet...

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Bibliographic Details
Main Authors: Nolwenn Legrand, Perla Salameh, Maxime Jullien, Patrice Chevallier, Enora Ferron, Gaelle David, Marie-Claire Devilder, Catherine Willem, Ketevan Gendzekhadze, Peter Parham, Christelle Retière, Katia Gagne
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cancers
Subjects:
KIR3DL1
null alleles
allelic polymorphism
haploidentical HSCT
relapse
leukemia
Online Access:https://www.mdpi.com/2072-6694/15/10/2754

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https://www.mdpi.com/2072-6694/15/10/2754

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