Systemic exosomal miR-193b-3p delivery attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage in mice

Systemic exosomal miR-193b-3p delivery attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage in mice

Abstract Background Inflammation is a potential crucial factor in the pathogenesis of subarachnoid hemorrhage (SAH). Circulating microRNAs (miRNAs) are involved in the regulation of diverse aspects of neuronal dysfunction. The therapeutic potential of miRNAs has been demonstrated in several CNS diso...

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Bibliographic Details
Main Authors: Niansheng Lai, Degang Wu, Tianyu Liang, Pengjie Pan, Guiqiang Yuan, Xiang Li, Haiying Li, Haitao Shen, Zhong Wang, Gang Chen
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Neuroinflammation
Subjects:
Subarachnoid hemorrhage
Neuroinflammation
Exosomes
Brain delivery
Online Access:http://link.springer.com/article/10.1186/s12974-020-01745-0

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http://link.springer.com/article/10.1186/s12974-020-01745-0

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