The influences of morphine or ketamine pre-treatment on hemodynamic, acid-base status, biochemical markers of brain damage and early survival in rats after asphyxial cardiac arrest

The influences of morphine or ketamine pre-treatment on hemodynamic, acid-base status, biochemical markers of brain damage and early survival in rats after asphyxial cardiac arrest

Abstract Background In different models of hypoxia, blockade of opioid or N-methyl-D-aspartate (NMDA) receptors shows cardio- and neuroprotective effects with a consequent increase in animal survival. The aim of the study was to investigate effects of pre-treatment with Morphine or Ketamine on hemod...

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Bibliographic Details
Main Authors: Vladimir Kuklin, Nurlan Akhatov, Timofei Kondratiev, Aidos Konkayev, Abai Baigenzhin, Maiya Konkayeva, Temirlan Karibekov, Nicholas Barlow, Torkjel Tveita, Vegard Dahl
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Anesthesiology
Subjects:
Morphine
Ketamine
Rats
Asphyxial cardiac arrest
Early survival
Online Access:http://link.springer.com/article/10.1186/s12871-019-0884-6

Internet

http://link.springer.com/article/10.1186/s12871-019-0884-6

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