β-carotene provides neuroprotection after experimental traumatic brain injury via the Nrf2-ARE pathway

β-carotene provides neuroprotection after experimental traumatic brain injury via the Nrf2-ARE pathway

We investigate whether β-carotene, a known natural antioxidant, can reduce oxidative stress induced by traumatic brain injury. In addition, we investigated the underlying mechanism of traumatic brain injury focusing on the NF-E2-related factor (Nrf2) pathway. A controlled cortical impact model was u...

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Bibliographic Details
Main Author: Peiqing Chen, Lin Li, Yongfeng Gao, Zhuqing Xie, Yin Zhang, Zhoujia Pan, Yingxin Tu, Hu Wang, Qiuqin Han, Xiamin Hu, Xiaoming Xin
Format: Article
Language:English
Published: IMR Press 2019-06-01
Series:Journal of Integrative Neuroscience
Subjects:
|traumatic brain injury|β-carotene|oxidative stress|nrf2-arc signaling pathway|mouse model
Online Access:https://jin.imrpress.com/fileup/1757-448X/PDF/1563257647415-644227975.pdf

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https://jin.imrpress.com/fileup/1757-448X/PDF/1563257647415-644227975.pdf

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