Development of a dual-component infection-resistant arterial replacement for small-caliber reconstructions: A proof-of-concept study

Development of a dual-component infection-resistant arterial replacement for small-caliber reconstructions: A proof-of-concept study

Introduction: Synthetic vascular grafts perform poorly in small-caliber (<6mm) anastomoses, due to intimal hyperplasia and thrombosis, whereas homografts are associated with limited availability and immunogenicity, and bioprostheses are prone to aneurysmal degeneration and calcification. Infe...

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Main Authors: Sonia Zia, Adrian Djalali-Cuevas, Michael Pflaum, Jan Hegermann, Daniele Dipresa, Panagiotis Kalozoumis, Artemis Kouvaka, Karin Burgwitz, Sofia Andriopoulou, Alexandros Repanas, Fabian Will, Karsten Grote, Claudia Schrimpf, Sotiria Toumpaniari, Marc Mueller, Birgit Glasmacher, Axel Haverich, Lucrezia Morticelli, Sotirios Korossis
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
small-caliber vascular graft
tibial artery
decellularized scaffold
polymeric sleeve
biomechanics
antimicrobial activity
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.957458/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2023.957458/full

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