Genomic characterization of a new phage BUCT541 against Klebsiella pneumoniae K1-ST23 and efficacy assessment in mouse and Galleria mellonella larvae

Over the past decades, the spread of multi-drug-resistant Klebsiella pneumoniae (MDR-KP) is becoming a new threat and new effective therapies against this pathogen are needed. Bacteriophage (phage) therapy is considered to be a promising alternative treatment for MDR-KP infections compared with anti...

Full description

Bibliographic Details
Main Authors: Mingfang Pu, Yahao Li, Pengjun Han, Wei Lin, Ronghua Geng, Fen Qu, Xiaoping An, Lihua Song, Yigang Tong, Shuyan Zhang, Zhen Cai, Huahao Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.950737/full