Single-cell RNA-seq uncovers distinct pathways and genes in endothelial cells during atherosclerosis progression

Single-cell RNA-seq uncovers distinct pathways and genes in endothelial cells during atherosclerosis progression

Background: Atherosclerosis (AS) is a chronic inflammatory disease involving various cell types, cytokines, and adhesion molecules. Herein, we aimed to uncover its key molecular mechanisms by single-cell RNA-seq (scRNA-seq) analysis.Methods: ScRNA-seq data of cells from atherosclerotic human coronar...

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Bibliographic Details
Main Authors: Min Wu, Yijin Wu, Shulin Tang, Jinsong Huang, Yueheng Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
atherosclerosis
single-cell RNA-seq
endothelial cells
fluid shear stress and atherosclerosis
TGF-beta
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1176267/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2023.1176267/full

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