OnTAD: hierarchical domain structure reveals the divergence of activity among TADs and boundaries

OnTAD: hierarchical domain structure reveals the divergence of activity among TADs and boundaries

Abstract The spatial organization of chromatin in the nucleus has been implicated in regulating gene expression. Maps of high-frequency interactions between different segments of chromatin have revealed topologically associating domains (TADs), within which most of the regulatory interactions are th...

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Bibliographic Details
Main Authors:	Lin An, Tao Yang, Jiahao Yang, Johannes Nuebler, Guanjue Xiang, Ross C. Hardison, Qunhua Li, Yu Zhang
Format:	Article
Language:	English
Published:	BMC 2019-12-01
Series:	Genome Biology
Online Access:	https://doi.org/10.1186/s13059-019-1893-y

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