CK2 Regulation: Perspectives in 2021

CK2 Regulation: Perspectives in 2021

The protein kinase CK2 (CK2) family encompasses a small number of acidophilic serine/threonine kinases that phosphorylate substrates involved in numerous biological processes including apoptosis, cell proliferation, and the DNA damage response. CK2 has also been implicated in many human malignancies...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Scott E. Roffey, David W. Litchfield
Формат:	Өгүүллэг
Хэл сонгох:	English
Хэвлэсэн:	MDPI AG 2021-09-01
Цуврал:	Biomedicines
Нөхцлүүд:	protein kinase CK2 casein kinase II CSNK2 phosphorylation post-translational modifications signal transduction
Онлайн хандалт:	https://www.mdpi.com/2227-9059/9/10/1361

Ижил төстэй зүйлс

Copper Modulates the Catalytic Activity of Protein Kinase CK2
-н: John E. Chojnowski, зэрэг
Хэвлэсэн: (2022-06-01)

In Skeletal Muscle Fibers, Protein Kinase Subunit CSNK2A1/CK2α Is Required for Proper Muscle Homeostasis and Structure and Function of Neuromuscular Junctions
-н: Mira Merholz, зэрэг
Хэвлэсэн: (2022-12-01)

Protein Kinase CK2 and Its Potential Role as a Therapeutic Target in Huntington’s Disease
-н: Angel White, зэрэг
Хэвлэсэн: (2022-08-01)

Exploring the CK2 Paradox: Restless, Dangerous, Dispensable
-н: Cinzia Franchin, зэрэг
Хэвлэсэн: (2017-01-01)

Editorial: Casein kinases in human diseases
-н: Andrea Venerando, зэрэг
Хэвлэсэн: (2022-12-01)

Chemical Genetic Validation of CSNK2 Substrates Using an Inhibitor-Resistant Mutant in Combination with Triple SILAC Quantitative Phosphoproteomics
-н: Laszlo Gyenis, зэрэг
Хэвлэсэн: (2022-06-01)

CK2 and the Hallmarks of Cancer
-н: May-Britt Firnau, зэрэг
Хэвлэсэн: (2022-08-01)

Divalent cation hinder the solubilization of a tubulin kinase activity from Trypanosoma cruzi epimastigotes
-н: GRACIELA UZCANGA, зэрэг
Хэвлэсэн: (2003-01-01)

Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2αLys198Arg
-н: Christian Werner, зэрэг
Хэвлэсэн: (2022-04-01)

Loss of Protein Kinase Csnk2b/CK2β at Neuromuscular Junctions Affects Morphology and Dynamics of Aggregated Nicotinic Acetylcholine Receptors, Neuromuscular Transmission, and Synaptic Gene Expression
-н: Nane Eiber, зэрэг
Хэвлэсэн: (2019-08-01)

Emerging roles of protein kinase CK2 in abscisic acid (ABA) signaling
-н: Belmiro eVilela, зэрэг
Хэвлэсэн: (2015-11-01)

Contribution of the CK2 Catalytic Isoforms α and α’ to the Glycolytic Phenotype of Tumor Cells
-н: Francesca Zonta, зэрэг
Хэвлэсэн: (2021-01-01)

Protein Kinase CK2α’, More than a Backup of CK2α
-н: Mathias Montenarh, зэрэг
Хэвлэсэн: (2023-12-01)

Role of protein kinase CK2 in antitumor drug resistance
-н: Christian Borgo, зэрэг
Хэвлэсэн: (2019-07-01)

Structural Hypervariability of the Two Human Protein Kinase CK2 Catalytic Subunit Paralogs Revealed by Complex Structures with a Flavonol- and a Thieno[2,3-d]pyrimidine-Based Inhibitor
-н: Karsten Niefind, зэрэг
Хэвлэсэн: (2017-01-01)

Targeting protein kinase CK2 in the treatment of cholangiocarcinoma
-н: Padma-Sheela Jayaraman
Хэвлэсэн: (2021-10-01)

Novel Nonphosphorylated Serine 9/21 GSK3β/a Antibodies: Expanding the Toolkit for Studying GSK3 Regulation
-н: Tessa Grabinski, зэрэг
Хэвлэсэн: (2016-11-01)

A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition
-н: Anastasia Barkova, зэрэг
Хэвлэсэн: (2022-11-01)

Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α′
-н: Jennifer Hochscherf, зэрэг
Хэвлэсэн: (2017-12-01)

The protein kinase CK2 catalytic domain from Plasmodium falciparum : crystal structure, tyrosine kinase activity and inhibition
-н: Ruiz-Carrillo, David, зэрэг
Хэвлэсэн: (2018)

A Synthetic Peptide, CK2.3, Inhibits RANKL-Induced Osteoclastogenesis through BMPRIa and ERK Signaling Pathway
-н: John Nguyen, зэрэг
Хэвлэсэн: (2020-07-01)

Impact of protein kinase CK2 downregulation and inhibition on oncomir clusters 17 ~ 92 and 106b ~ 25 in prostate, breast, and head and neck cancers
-н: Betsy T. Kren, зэрэг
Хэвлэсэн: (2024-10-01)

Protein Kinase CK2 and Epstein–Barr Virus
-н: Mathias Montenarh, зэрэг
Хэвлэсэн: (2023-01-01)

Exploring the Activity of Fungal Phenalenone Derivatives as Potential CK2 Inhibitors Using Computational Methods
-н: Sabrin R. M. Ibrahim, зэрэг
Хэвлэсэн: (2022-04-01)

Analysis of the phosphoproteome of CK2α(–/–)/Δα′ C2C12 myoblasts compared to the wild-type cells
-н: Christian Borgo, зэрэг
Хэвлэсэн: (2023-02-01)

Comprehensive Characterization of CK1δ-Mediated Tau Phosphorylation in Alzheimer’s Disease
-н: Aileen Roth, зэрэг
Хэвлэсэн: (2022-06-01)

Protein kinase 2 (CK2): a potential regulator of immune cell development and function in cancer
-н: Kazim Husain, зэрэг
Хэвлэсэн: (2021-07-01)

Targeting of Protein Kinase CK2 Elicits Antiviral Activity on Bovine Coronavirus Infection
-н: Ailyn C. Ramón, зэрэг
Хэвлэсэн: (2022-03-01)

Comparing Two Neurodevelopmental Disorders Linked to CK2: Okur-Chung Neurodevelopmental Syndrome and Poirier-Bienvenu Neurodevelopmental Syndrome—Two Sides of the Same Coin?
-н: Demetra Ballardin, зэрэг
Хэвлэсэн: (2022-05-01)

Novel small molecule protein kinase CK2 inhibitors exert potent antitumor effects on T98G and SEGA cells in vitro
-н: Emanuela Pucko, зэрэг
Хэвлэсэн: (2019-09-01)

Identification of casein kinase 1, casein kinase 2, and cAMP-dependent protein kinase-like activities in Trypanosoma evansi
-н: José Manuel Galán-Caridad, зэрэг
Хэвлэсэн: (2004-12-01)

The Immune Regulatory Role of Protein Kinase CK2 and Its Implications for Treatment of Cancer
-н: Huixian Hong, зэрэг
Хэвлэсэн: (2021-12-01)

Minor Kinases with Major Roles in Cytokinesis Regulation
-н: Stefano Sechi, зэрэг
Хэвлэсэн: (2022-11-01)

Casein kinase II is required for proper cell division and acts as a negative regulator of centrosome duplication in Caenorhabditis elegans embryos
-н: Jeffrey C. Medley, зэрэг
Хэвлэсэн: (2017-01-01)

Histone H3 threonine 11 phosphorylation by Sch9 and CK2 regulates chronological lifespan by controlling the nutritional stress response
-н: Seunghee Oh, зэрэг
Хэвлэсэн: (2018-06-01)

In Vitro Identification of Phosphorylation Sites on TcPolβ by Protein Kinases TcCK1, TcCK2, TcAUK1, and TcPKC1 and Effect of Phorbol Ester on Activation by TcPKC of TcPolβ in <i>Trypanosoma cruzi</i> Epimastigotes
-н: Edio Maldonado, зэрэг
Хэвлэсэн: (2024-04-01)

Phosphorylation Affects DNA-Binding of the Senescence-Regulating bZIP Transcription Factor GBF1
-н: Anja Smykowski, зэрэг
Хэвлэсэн: (2015-09-01)

Identification of high protein kinase CK2α in HPV(+) oropharyngeal squamous cell carcinoma and correlation with clinical outcomes
-н: Janeen H. Trembley, зэрэг
Хэвлэсэн: (2021-12-01)

CK1δ/ε-mediated TDP-43 phosphorylation contributes to early motor neuron disease toxicity in amyotrophic lateral sclerosis
-н: Vivian I. Ko, зэрэг
Хэвлэсэн: (2024-12-01)

CK2 and protein kinases of the CK1 superfamily as targets for neurodegenerative disorders
-н: Andrea Baier, зэрэг
Хэвлэсэн: (2022-10-01)