Zng1 is a GTP-dependent zinc transferase needed for activation of methionine aminopeptidase

Zng1 is a GTP-dependent zinc transferase needed for activation of methionine aminopeptidase

Summary: The evolution of zinc (Zn) as a protein cofactor altered the functional landscape of biology, but dependency on Zn also created an Achilles’ heel, necessitating adaptive mechanisms to ensure Zn availability to proteins. A debated strategy is whether metallochaperones exist to prioritize ess...

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Bibliographic Details
Main Authors: Miriam Pasquini, Nicolas Grosjean, Kim K. Hixson, Carrie D. Nicora, Estella F. Yee, Mary Lipton, Ian K. Blaby, John D. Haley, Crysten E. Blaby-Haas
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Cell Reports
Subjects:
MetAP
insertase
NME
GTPase
zinc homeostasis
nutrient limitation
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722006076

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http://www.sciencedirect.com/science/article/pii/S2211124722006076

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