Rational Design and Characterization of Trispecific Antibodies Targeting the HIV-1 Receptor and Envelope Glycoprotein

Rational Design and Characterization of Trispecific Antibodies Targeting the HIV-1 Receptor and Envelope Glycoprotein

Multitudinous broadly neutralizing antibodies (bNAbs) against HIV-1 have been developed as novel antiviral prophylactic and therapeutic agents. Combinations of bNAbs are generally even more effective than when they are applied individually, showing excellent neutralization coverage and limiting the...

Full description

Bibliographic Details
Main Authors: Jinhu Liang, Linlin Zhai, Zuxin Liang, Xiaoling Chen, Yushan Jiang, Yuanlong Lin, Shiyan Feng, Yingxia Liu, Wei Zhao, Fuxiang Wang
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Vaccines
Subjects:
HIV-1
neutralizing antibodies
trispecific antibodies
host receptor CD4
CCR5
Online Access:https://www.mdpi.com/2076-393X/12/1/19

Internet

https://www.mdpi.com/2076-393X/12/1/19

Similar Items