Radiolabeled Cetuximab Conjugates for EGFR Targeted Cancer Diagnostics and Therapy

Radiolabeled Cetuximab Conjugates for EGFR Targeted Cancer Diagnostics and Therapy

The epidermal growth factor receptor (EGFR) has evolved over years into a main molecular target for the treatment of different cancer entities. In this regard, the anti-EGFR antibody cetuximab has been approved alone or in combination with: (a) chemotherapy for treatment of colorectal and head and...

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Bibliographic Details
Main Authors: Wiebke Sihver, Jens Pietzsch, Mechthild Krause, Michael Baumann, Jörg Steinbach, Hans-Jürgen Pietzsch
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Pharmaceuticals
Subjects:
EGFR
radiolabeled cetuximab conjugates
radioimmunotherapy (RIT)
cancer theranostics
external beam radiotherapy (EBRT)
endoradionuclide therapy
Online Access:http://www.mdpi.com/1424-8247/7/3/311

Internet

http://www.mdpi.com/1424-8247/7/3/311

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