Pathophysiological Investigation of Skeletal Deformities of Musculocontractural Ehlers–Danlos Syndrome Using Induced Pluripotent Stem Cells

Pathophysiological Investigation of Skeletal Deformities of Musculocontractural Ehlers–Danlos Syndrome Using Induced Pluripotent Stem Cells

Musculocontractural Ehlers–Danlos syndrome caused by mutations in the carbohydrate sulfotransferase 14 gene (mcEDS-<i>CHST14</i>) is a heritable connective tissue disorder characterized by multiple congenital malformations and progressive connective tissue fragility-related manifestation...

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Bibliographic Details
Main Authors: Fengming Yue, Takumi Era, Tomomi Yamaguchi, Tomoki Kosho
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Genes
Subjects:
musculocontractural Ehlers–Danlos syndrome
<i>CHST14</i> (carbohydrate sulfotransferase 14)
skeletal deformities
induced pluripotent stem cells (iPSCs)
in vitro assessment
impaired osteogenesis
Online Access:https://www.mdpi.com/2073-4425/14/3/730

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https://www.mdpi.com/2073-4425/14/3/730

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