hrHPV E5 oncoprotein: immune evasion and related immunotherapies

Abstract The immune response is a key factor in the fight against HPV infection and related cancers, and thus, HPV is able to promote immune evasion through the expression of oncogenes. In particular, the E5 oncogene is responsible for modulation of several immune mechanisms, including antigen prese...

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Bibliographic Details
Main Authors: Antonio Carlos de Freitas, Talita Helena Araújo de Oliveira, Marconi Rego Barros, Aldo Venuti
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-017-0541-1