Nucleotide Composition of Ultra-Conserved Elements Shows Excess of GpC and Depletion of GG and CC Dinucleotides

Nucleotide Composition of Ultra-Conserved Elements Shows Excess of GpC and Depletion of GG and CC Dinucleotides

The public UCNEbase database, comprising 4273 human ultra-conserved noncoding elements (UCNEs), was thoroughly investigated with the aim to find any nucleotide signals or motifs that have made these DNA sequences practically unchanged over three hundred million years of evolution. Each UCNE comprise...

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Bibliographic Details
Main Authors: Larisa Fedorova, Oleh A. Mulyar, Jan Lim, Alexei Fedorov
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Genes
Subjects:
computational biology
polymorphism
genetic variation
evolution
DNA structure
bioinformatics
Online Access:https://www.mdpi.com/2073-4425/13/11/2053

Internet

https://www.mdpi.com/2073-4425/13/11/2053

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