Nucleotide Composition of Ultra-Conserved Elements Shows Excess of GpC and Depletion of GG and CC Dinucleotides
The public UCNEbase database, comprising 4273 human ultra-conserved noncoding elements (UCNEs), was thoroughly investigated with the aim to find any nucleotide signals or motifs that have made these DNA sequences practically unchanged over three hundred million years of evolution. Each UCNE comprise...
Main Authors: | Larisa Fedorova, Oleh A. Mulyar, Jan Lim, Alexei Fedorov |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
|
Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/13/11/2053 |
Similar Items
-
Profound Non-Randomness in Dinucleotide Arrangements within Ultra-Conserved Non-Coding Elements and the Human Genome
by: Larisa Fedorova, et al.
Published: (2023-08-01) -
Synonymous Dinucleotide Usage: A Codon-Aware Metric for Quantifying Dinucleotide Representation in Viruses
by: Spyros Lytras, et al.
Published: (2020-04-01) -
1000 human genomes carry widespread signatures of GC biased gene conversion
by: Rajib Dutta, et al.
Published: (2018-04-01) -
Global Picture of Genetic Relatedness and the Evolution of Humankind
by: Gennady V. Khvorykh, et al.
Published: (2020-11-01) -
Analysis of Common SNPs across Continents Reveals Major Genomic Differences between Human Populations
by: Larisa Fedorova, et al.
Published: (2022-08-01)