Fatal Breakthrough Candidemia in an Immunocompromised Patient in Kuwait Due to <i>Candida auris</i> Exhibiting Reduced Susceptibility to Echinocandins and Carrying a Novel Mutation in Hotspot-1 of <i>FKS1</i>

Fatal Breakthrough Candidemia in an Immunocompromised Patient in Kuwait Due to <i>Candida auris</i> Exhibiting Reduced Susceptibility to Echinocandins and Carrying a Novel Mutation in Hotspot-1 of <i>FKS1</i>

<i>Candida auris</i> is an emerging yeast pathogen that has recently caused major outbreaks in healthcare facilities worldwide. Clinical <i>C. auris</i> isolates are usually resistant to fluconazole and readily develop resistance to echinocandins and amphotericin B (AMB) duri...

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Bibliographic Details
Main Authors: Inaam Al-Obaid, Mohammad Asadzadeh, Suhail Ahmad, Khaled Alobaid, Wadha Alfouzan, Ritu Bafna, Maha Emara, Leena Joseph
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Journal of Fungi
Subjects:
<i>C. auris</i>
breakthrough candidemia
echinocandin resistance
hotspot-1 of <i>FKS1</i>
S639T mutation
immunocompromised patient
Online Access:https://www.mdpi.com/2309-608X/8/3/267

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https://www.mdpi.com/2309-608X/8/3/267

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