Inhibitory effect of aloperine on transient outward potassium currents in rat cardiac myocytes

Inhibitory effect of aloperine on transient outward potassium currents in rat cardiac myocytes

Objective:Aloperine (ALO) is an effective quinolizidine alkaloid. Previous research has demonstrated its antiarrhythmic effect by inhibiting voltage-gated sodium currents in rat ventricular myocytes. This study explored its effect on transient outward potassium currents (Ito) in rat atrial myocytes...

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Bibliographic Details
Main Authors: Xiao-Na Dong, Meng-Ting Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Pharmacology
Subjects:
aloperine
transient outward potassium current
whole-cell patch-clamp
atrial fibrillation
molecular docking
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1372973/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1372973/full

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