Standardization and application of a modified RFLP-PCR methodology for analysis of polymorphisms linked to treatment resistance in Ancylostoma braziliense

Standardization and application of a modified RFLP-PCR methodology for analysis of polymorphisms linked to treatment resistance in Ancylostoma braziliense

Abstract Background Single nucleotide polymorphisms (SNPs) in codons 167, 198 and 200 of the beta-tubulin isotype 1 gene are associated with benzimidazoles resistance in many helminths. Codon 167 mutation has never been described in hookworms; however, polymorphisms in codons 198 and 200 have been d...

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Bibliographic Details
Main Authors: Luis Fernando Viana Furtado, João Guilherme Scarpelli Magalhães, Élida Mara Leite Rabelo
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Parasites & Vectors
Subjects:
Hookworm
Ancylostoma braziliense
Resistance
Beta-tubulin
Online Access:http://link.springer.com/article/10.1186/s13071-018-3125-9

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http://link.springer.com/article/10.1186/s13071-018-3125-9

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