Transcriptional signals of transformation in human cancer

Transcriptional signals of transformation in human cancer

Abstract Background As normal cells transform into cancers, their cell state changes, which may drive cancer cells into a stem-like or more primordial, foetal, or embryonic cell state. The transcriptomic profile of this final state may encode information about cancer’s origin and how cancers relate...

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Main Authors: Gerda Kildisiute, Maria Kalyva, Rasa Elmentaite, Stijn van Dongen, Christine Thevanesan, Alice Piapi, Kirsty Ambridge, Elena Prigmore, Muzlifah Haniffa, Sarah A. Teichmann, Karin Straathof, Isidro Cortés-Ciriano, Sam Behjati, Matthew D. Young
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Genome Medicine
Online Access:https://doi.org/10.1186/s13073-023-01279-z

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https://doi.org/10.1186/s13073-023-01279-z

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