Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling

Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling

Summary: Natural control of HIV-1 is a characteristic of <1% of HIV-1-infected individuals, so called elite controllers (EC). In this study, we sought to identify signaling pathways associated with the EC phenotype using integrative proteo-transcriptomic analysis and immunophenotyping. We found H...

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Bibliographic Details
Main Authors: Sara Svensson Akusjärvi, Anoop T. Ambikan, Shuba Krishnan, Soham Gupta, Maike Sperk, Ákos Végvári, Flora Mikaeloff, Katie Healy, Jan Vesterbacka, Piotr Nowak, Anders Sönnerborg, Ujjwal Neogi
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:iScience
Subjects:
Glycobiology
Molecular biology
Immunology
Virology
Omics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221015777

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221015777

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