Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson’s disease patients

Abstract Background Parkinson’s disease (PD) presently is conceptualized as a protein aggregation disease in which pathology involves both the enteric and the central nervous system, possibly spreading from one to another via the vagus nerves. As gastrointestinal dysfunction often precedes or parall...

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Bibliographic Details
Main Authors: J. R. Bedarf, F. Hildebrand, L. P. Coelho, S. Sunagawa, M. Bahram, F. Goeser, P. Bork, U. Wüllner
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Genome Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13073-017-0428-y