The KiSS-1/GPR54 system: Essential roles in physiological homeostasis and cancer biology
KiSS-1, first identified as an anti-metastasis gene in melanoma, encodes C-terminally amidated peptide products, including kisspeptin-145, kisspeptin-54, kisspeptin-14, kisspeptin-13 and kisspeptin-10. These products are endogenous ligands coupled to G protein-coupled receptor 54 (GPR54)/hOT7T175/AX...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2022-01-01
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Series: | Genes and Diseases |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S235230422030091X |