Tumor biomechanics as a novel imaging biomarker to assess response to immunotherapy in a murine glioma model

Tumor biomechanics as a novel imaging biomarker to assess response to immunotherapy in a murine glioma model

Abstract Glioblastoma is the most common and aggressive primary malignant brain tumor with poor prognosis. Novel immunotherapeutic approaches are currently under investigation. Even though magnetic resonance imaging (MRI) is the most important imaging tool for treatment monitoring, response assessme...

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Bibliographic Details
Main Authors: Yannik Streibel, Michael O. Breckwoldt, Jessica Hunger, Chenchen Pan, Manuel Fischer, Verena Turco, Berin Boztepe, Hannah Fels-Palesandro, Jonas G. Scheck, Volker Sturm, Kianush Karimian-Jazi, Dennis A. Agardy, Giacomo Annio, Rami Mustapha, Shreya S. Soni, Abdulrahman Alasa, Ina Weidenfeld, Christopher B. Rodell, Wolfgang Wick, Sabine Heiland, Frank Winkler, Michael Platten, Martin Bendszus, Ralph Sinkus, Katharina Schregel
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Scientific Reports
Subjects:
MR elastography
Glioma
Immunotherapy
Tumor stiffness
Tissue biomechanics
Online Access:https://doi.org/10.1038/s41598-024-66519-7

Internet

https://doi.org/10.1038/s41598-024-66519-7

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