Identification and quantification of protein nitration sites in human coronary artery smooth muscle cells in the absence and presence of peroxynitrous acid/peroxynitrite

Identification and quantification of protein nitration sites in human coronary artery smooth muscle cells in the absence and presence of peroxynitrous acid/peroxynitrite

Peroxynitrous acid/peroxynitrite (ONOOH/ONOO−) is a powerful oxidizing/nitrating system formed at sites of inflammation, which can modify biological targets, and particularly proteins. Here, we show that multiple proteins from primary human coronary artery smooth muscle cells are nitrated, with LC-M...

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Bibliographic Details
Main Authors: Shuqi Xu, Christine Y. Chuang, Clare L. Hawkins, Per Hägglund, Michael J. Davies
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Redox Biology
Subjects:
Peroxynitrite
Nitration
Oxidation
Smooth muscle cell
3-Nitrotyrosine
Extracellular matrix
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723002008

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http://www.sciencedirect.com/science/article/pii/S2213231723002008

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