Whole human genome 5’-mC methylation analysis using long read nanopore sequencing

Methylation microarray and bisulphite sequencing are often used to study 5’-methylcytosine (5’-mC) modification of CpG dinucleotides in the human genome. Although both technologies produce trustworthy results, the evaluation of the methylation status of CpG sites suffers from the potential side effe...

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Bibliographic Details
Main Authors: Catarina Silva, Miguel Machado, José Ferrão, António Sebastião Rodrigues, Luís Vieira
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Epigenetics
Subjects:
Online Access:http://dx.doi.org/10.1080/15592294.2022.2097473