Steroidogenic Factor 1, a Goldilocks Transcription Factor from Adrenocortical Organogenesis to Malignancy

Steroidogenic Factor 1, a Goldilocks Transcription Factor from Adrenocortical Organogenesis to Malignancy

Steroidogenic factor-1 (SF-1, also termed Ad4BP; NR5A1 in the official nomenclature) is a nuclear receptor transcription factor that plays a crucial role in the regulation of adrenal and gonadal development, function and maintenance. In addition to its classical role in regulating the expression of...

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Bibliographic Details
Main Authors: Lauriane Relav, Mabrouka Doghman-Bouguerra, Carmen Ruggiero, João C. D. Muzzi, Bonald C. Figueiredo, Enzo Lalli
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
steroidogenic factor 1
transcription factors
nuclear receptors
adrenal cortex
steroidogenesis
gene dosage
Online Access:https://www.mdpi.com/1422-0067/24/4/3585

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https://www.mdpi.com/1422-0067/24/4/3585

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