LncRNA LINC00205 stimulates osteoporosis and contributes to spinal fracture through the regulation of the miR-26b-5p/KMT2C axis

LncRNA LINC00205 stimulates osteoporosis and contributes to spinal fracture through the regulation of the miR-26b-5p/KMT2C axis

Abstract Background Osteoporosis (OP) is a common bone disease marked by decreased bone strength. Increasing evidence suggests that long non-coding RNA (lncRNAs) play important roles in the occurrence and progression of OP. This study aimed to investigate the role and mechanism of LINC00205 in the o...

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Bibliographic Details
Main Authors: Hongtao Wang, Weilin Xu, Xiaoqing Chen, Xiongfeng Mei, Zhonghua Guo, Juan Zhang
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Musculoskeletal Disorders
Subjects:
lncRNA LINC00205
Osteoporosis
Spinal fracture
miR-26b-5p
KMT2C
Human mesenchymal stem cells
Online Access:https://doi.org/10.1186/s12891-023-06136-z

Internet

https://doi.org/10.1186/s12891-023-06136-z

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