266 Decoding the role of polyamine metabolism on anti-tumor immunity in head and neck cancer

OBJECTIVES/GOALS: The effect of immunosuppressive metabolites on anti-tumor immunity in human papillomavirus (HPV)-associated vs carcinogen-driven head and neck cancer is unknown. The objective of this study is to define the extent to which metabolites impair this response and identify novel metabol...

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Bibliographic Details
Main Authors: Richard Alexander Harbison, William Andrews, Michael Mikula, Aleksandra Ogurtsova, Liz Engle, Ogechi Nwankwoala, Reagan Willis, Pritam Sadhukhan, Mark Burns, Drew Pardoll, Tanguy Seiwert, Carole Fakhry, Robert A. Casero, Elana Fertig, Erika Pearce
Format: Article
Language:English
Published: Cambridge University Press 2023-04-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866123003254/type/journal_article