Postnatal nutrition environment reprograms renal DNA methylation patterns in offspring of maternal protein-restricted stroke-prone spontaneously hypertensive rats

Postnatal nutrition environment reprograms renal DNA methylation patterns in offspring of maternal protein-restricted stroke-prone spontaneously hypertensive rats

Maternal malnutrition hampers the offspring health by manipulating the epigenome. Recent studies indicate that the changes in DNA methylation could be reversed by afterbirth nutrition supplementation. In this study, we used DNA methylation arrays to comprehensively investigate the DNA methylation st...

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Bibliographic Details
Main Authors: Chika Ando, Sihui Ma, Moe Miyoshi, Kyohei Furukawa, Xuguang Li, Huijuan Jia, Hisanori Kato
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Nutrition
Subjects:
DNA methylation
epigenetics
gene expression
hypertension
kidney
maternal protein restriction
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2023.1134955/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2023.1134955/full

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