Therapeutic targeting of circ‐CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression

Therapeutic targeting of circ‐CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression

Abstract Aerobic glycolysis is a hallmark of metabolic reprogramming in tumor progression. However, the mechanisms regulating glycolytic gene expression remain elusive in neuroblastoma (NB), the most common extracranial malignancy in childhood. Herein, we identify that CUT‐like homeobox 1 (CUX1) and...

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Bibliographic Details
Main Authors: Huanhuan Li, Feng Yang, Anpei Hu, Xiaojing Wang, Erhu Fang, Yajun Chen, Dan Li, Huajie Song, Jianqun Wang, Yanhua Guo, Yang Liu, Hongjun Li, Kai Huang, Liduan Zheng, Qiangsong Tong
Format: Article
Language:English
Published: Springer Nature 2019-12-01
Series:EMBO Molecular Medicine
Subjects:
circular RNA
CUT‐like homeobox 1
EWS RNA‐binding protein 1
MYC‐associated zinc finger protein
tumor progression
Online Access:https://doi.org/10.15252/emmm.201910835

Internet

https://doi.org/10.15252/emmm.201910835

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